On this episode of Pelvic Pain unPacked, we sit down with Dr. James Pfaus, Assistant Professor at Charles University in Prague and an internationally recognized behavioral neuroscientist, to explore what the science really says about cannabis, pelvic health, and sexual function. We talk through how the brain balances excitation and inhibition, and Dr. Pfaus explains the roles of key neurotransmitters like dopamine, serotonin, and endogenous opioids.
We discuss how chronic pelvic symptoms and anticipatory discomfort can shift the nervous system into protection mode, changing how touch is experienced and how the pelvic floor responds. Listeners will learn where THC may help with sexual desire and orgasm, why dose and timing matter so much, and how individual differences and product variability influence real-world experiences with cannabis and sexual well-being.
In this episode, you will hear:
- How the brain balances excitation and inhibition in sexual response
- Role of dopamine, serotonin, endogenous opioids, and endocannabinoids in desire and arousal
- Chronic pelvic symptoms, anticipatory discomfort, and protective nervous system responses
- Pelvic floor tension, hypersensitivity, and their impact on sexual experiences
- Challenges with dosing, edibles, and product variability in cannabis use for sexual function
Resources from this Episode
- Effects of Cannabinoids on Female Sexual Function — PubMed: https://pubmed.ncbi.nlm.nih.gov/31521567/?utm_source=chatgpt.com
- ACOG: Cannabis Products for Pain Associated With Gynecologic Conditions: https://www.acog.org/clinical/clinical-guidance/clinical-consensus/articles/2024/07/the-use-of-cannabis-products-for-the-management-of-pain-associated-with-gynecologic-conditions?utm_source=chatgpt.com
- IASP: Cannabis, Cannabinoids and Pain Management Research Agenda: https://pmc.ncbi.nlm.nih.gov/articles/PMC8855877/?utm_source=chatgpt.com
- Cannabis and Male Sexual Function — PubMed: https://pubmed.ncbi.nlm.nih.gov/32561331/?utm_source=chatgpt.com
- Medical Cannabis/Cannabinoids for Chronic Pain — BMJ: https://www.bmj.com/content/374/bmj.n1034?utm_source=chatgpt.com
Disclaimer:
The information shared in this podcast is intended for educational and informational purposes only and should not be considered medical advice. It is not intended to diagnose, treat, cure, or prevent any disease or medical condition. The views and opinions expressed are those of the individual participants and do not necessarily reflect the views, policies, or positions of MedRoots or the medical community at large. Listeners should consult a qualified healthcare professional before making any healthcare-related decisions.
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